Basic Information On Clodronate Liposome

For you to know about the clodronate liposome therapy, you should know a little about cells in the body. Your liposomes are little vesicles found throughout the body that contain lipids and tiny water based areas. Macrophages are the basic cells of all immune systems in a human. The liposomes interact with macrophages to cause them to kill off intruders. They can be changed with medication to affect how the macrophage will work.

The clodronate is a drug that is classified as biophosphate. It can keep your bones from taking on a secondary cancer. Secondary cancers are those that have metastasized or spread from the original site and turned into a different kind of cancer.



When secondary cancers attack the bone, it weakens the bone structure and takes away calcium and flushes it into the blood which is called hypercalcemia. It could make confusion, nausea and being irritated easily a new way of life. The clodronate helps eliminate this by keeping the calcium levels in the blood normal.

Osteoblasts and osteoclasts are two kinds of cells that keep your bones healthy by helping to rebuild them. Some kinds of cancers will put off chemicals that cause osteoclasts to become severely overworked and allows the bones to get weak. The medication goes right to the areas that are becoming weak due to this activity.

It attacks the higher activity areas and causes the cells to react in a normal way, therefore causing the cancer to not be able to spread and attack other healthy cells. In this respect, the bones stop losing calcium and are able to become strong again to fight off the cancer cells. It could be beneficial to those with bone cancers to undergo this type of treatment, and it should be discussed with your oncologist and physician.

The pills can be taken two times daily with no food. Administration should be at least two hours prior to or after medications and all foods including dairy products. If not followed, interference with absorption could be an issue so it is best to adhere to the recommended dosage times to keep the best blood levels.

Some common side effects could include nausea, diarrhea, hypocalcemia or calcium levels that are too low. The latter could cause the tongue and lips to tingle, and is very rare. Kidneys could lower in complete functioning, and osteonecrosis has also been seen. This is a condition where the healthy areas in the jaw takes damage and therefore dies. To avoid the possibility of this occurring, it is wise to care for teeth regularly while on the medication and keep your dentist in the loop about this medication being part of your regiment.

There are other pharmaceutical names that the clodronate liposome treatment is known by. You can discuss with your doctor how it works in your body and how long you can expect the treatment to last based on your personal history. Some people are not candidates for this medication. You should ask about the good and bad about the treatment prior to exhausting other options.